Detalhe da pesquisa
1.
SnapShot: Antimalarial Drugs.
Cell
; 183(2): 554-554.e1, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33064992
2.
Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii.
Proc Natl Acad Sci U S A
; 116(52): 26881-26891, 2019 Dec 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31806760
3.
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Antimicrob Agents Chemother
; 65(11): e0031121, 2021 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34460304
4.
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.
PLoS Pathog
; 15(6): e1007722, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31170268
5.
Efficacy of post-harvest rinsing and bleach disinfection of E. coli O157:H7 on spinach leaf surfaces.
Food Microbiol
; 62: 212-220, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-27889151
6.
Antiplasmodial peptaibols act through membrane directed mechanisms.
Cell Chem Biol
; 31(2): 312-325.e9, 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37995692
7.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun
; 15(1): 937, 2024 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-38297033
8.
Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance.
Elife
; 122023 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37737220
9.
Human Polo-like Kinase Inhibitors as Antiplasmodials.
ACS Infect Dis
; 9(4): 1004-1021, 2023 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36919909
10.
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum.
Nat Commun
; 14(1): 3059, 2023 05 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37244916
11.
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target.
Sci Transl Med
; 15(686): eadc9249, 2023 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36888694
12.
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Br J Pharmacol
; 180(15): 1899-1929, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37197802
13.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Res Sq
; 2023 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37546892
14.
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
Nat Commun
; 13(1): 4976, 2022 08 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36008486
15.
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Sci Transl Med
; 14(667): eabo7219, 2022 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36260689
16.
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.
Cell Chem Biol
; 29(2): 191-201.e8, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34348113
17.
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.
Commun Biol
; 5(1): 128, 2022 02 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35149760
18.
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science
; 376(6597): 1074-1079, 2022 06 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35653481
19.
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum.
ACS Infect Dis
; 7(4): 811-825, 2021 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33715347
20.
Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials.
ACS Infect Dis
; 6(4): 613-628, 2020 04 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32078764